Cytochalasin B-induced morphological changes of Ehrlich ascites tumor cells

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A scanning electron microscopic study of the two-step effect of cytochalasin B on Ehrlich ascites tumor cells.

The effect of cytochalasin B (CB) on the surface structure of Ehrlich ascites tumor cells was investigated using the scanning electron microscope. The effect occurs in two steps: formation of zeiotic knobs on the cell surface and subsequent grouping of the knobs at one pole of the cell. The early step of zeiotic knob formation occurs at low concentrations of CB (0.5-1 microgram/ml) at 37 degree...

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ژورنال

عنوان ژورنال: Okayama Igakkai Zasshi (Journal of Okayama Medical Association)

سال: 1983

ISSN: 0030-1558,1882-4528

DOI: 10.4044/joma1947.95.1-2_41